ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis

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ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis.

Genetic variation at the ABCG5/G8 locus has been associated with markers of cholesterol homeostasis. As data originate from small-scale studies, we performed a meta-analysis to study these associations in a large dataset. We first investigated associations between five common ABCG5/G8 polymorphisms (p.Q604E, p.D19H, p.Y54C, p.T400K, and p.A632V) and plasma sterol levels in 245 hypercholesterola...

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 2010

ISSN: 0022-2275

DOI: 10.1194/jlr.m008128